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Original Article
Plasma Amino Acid Patterns in Reye's Syndrome.
Han Wook Yoo, Hee Shang Youn
Clin Exp Pediatr. 1989;32(10):1377-1383.   Published online October 31, 1989
The metabolic disturbances of Reye’s syndrome are many and involve carbohydrates, amino acids, free fatty acids, proteins, ammonia and acid-base balance. It has been suggested that the derangement of mitochondrial integrity by an agent or agents unknown leads to a loss of enzyme activity in many metabolic pathways in which t노e mitochondria are involoved. Of primary interests in this study is the abnormalities regarding...
A Study on the Change of Plasma Renin Activity(PRA) and Aldosterone Concentration(PAC) before and after Heart Operation in Children with Congenital Heart Disease.
Jae Hong You, Jae Ho Lee
Clin Exp Pediatr. 1989;32(9):1232-1239.   Published online September 30, 1989
Thes is a study on changes of plasma renin activity (PRA) and aldosterone concentration (PAC) which was obtained before and after heart operation in 26 normotensive children with congenital heart diseases without renal disease admitted in Chungnam National University Hospital for cardiac catheterization with angiogram and heart operation from Apr. 1988 to Aug. 1988 to confirm any differences of PRA and PAC between groups...
Continous Wave Dopple Echocardiographic Prediction of Pulmonary Arterial Hupertension in Congenital Heart Disease.
Jung Suk Lee, Mi Jung Ko, Yeon Gyun Oh, Hyang Suk Yoon
Clin Exp Pediatr. 1989;32(7):951-957.   Published online July 31, 1989
This study determines the accuracy of Doppler echocardiography for predicting the presence of pulmonary artery hypertension from Doppler pulmonary artery velocity traces. The patient group included 26 patients with congenital cardiac disease who had undergone catheterization. Doppler measurements of acceleration time(AT), right ventricular ejection time (RVET), and AT/ RVET were compared with pulmonary artery pressure (PAP) and mean pulmonary artery pressure (m-PAP). We devided the patients in...
Comparisons of the Ratio of Pulmonary to Systemic Blood Flow(Qp/Qs) Determined by Non-invasive Doppler Echocardiography and Radionuclide-Angiocardiography in Congenital Heart Diseases.
Jung Suk Lee, Chul Wo Park, Hyang Suk Yoon
Clin Exp Pediatr. 1989;32(7):943-950.   Published online July 31, 1989
This study was desinged to assess the accuracy of the ratio of pulmonary to systemic blood flow (Qp/Qs) measured by non-invasive continuous wave (CW) Doppler echocardiography comparing with other non-invasive Radionu- clide Angiocardiography (RNA) and invasive Fick method. Seventeen children with congenital heart disease, aged 14 months to 15 years, admitted for cardiac opention to this hospital, were studied. High correlations were found between the...
A Clinical Study on Children with Acute Glomerulonephritis.
Jeong Ok Kim, Son Moon Shin, Yong Hoon Park
Clin Exp Pediatr. 1989;32(6):779-788.   Published online June 30, 1989
A clinical observation has been made on 111 children with acute glomerulonephritis who were admitted to Pediatric Department of Yeungnam University Hospital during 5 years period from June 1, 1983 to May 31, 1988. The incidence of acute glomerulonephritis among hospitalized patients was 1.59% and the annual incidence was decreased markedly after June 1986. Peak incidence was noticed in the wintertime from November to January...
Continuous Arteriovenous Hemofiltration in Children.
Hae Il Cheong, Dong Kyu Jin, Young Seo park, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1989;32(2):230-238.   Published online February 28, 1989
Among those who were admitted to the Pediatric Intensive Care Unit (PICU), Seoul National University Children’s Hospital and developed acute renal failure (ARF) during the disease course, 11 children received continuous arteriovenous hemofiltration (CAVH) by pediatricians during a 3-year- period from Nov. 85 to Oct. 88. Their clinical findings were analyzed retrospectively, and the results were as follows; 1) They were 5 boys and 6...
Comparative Study of the Abilities of Visual Motor Integration in Korea Children to That of Berry's Results.
Chang Jun Coe, Young Hyuk Lee
Clin Exp Pediatr. 1989;32(2):191-197.   Published online February 28, 1989
Visual.Motor Integration (VMI) test, designed by Beery, is one of the battery, which is commomly used in investigating the developmental status of child. As the test was designed for American children, the test may be not feasible for Korean children because of difference of cultural back. ground, race as well as econornic status. 1674 normal Korean children aged from 5 to 12 were tested...
Perforation of the Gastointestinal Tract in Infancy and Childhood.
S J Lee, Y S Kim, H D Cha, T C Kwon, C M Kang
Clin Exp Pediatr. 1988;31(12):1626-1632.   Published online December 31, 1988
Thirty-nine patients with perforations of the gastrointestinal tract proved by operation were presented. 35.9% of perforations were between the age of 6-10 year and 20.5% were Neonates. Male to female ratio was 2:1. The cardinal symptom of the perforation was abdominal pain in older child and abdominal distention in the neonates. Abdominal X-ray showed subphrenic free air shadow in 48.7% of the total cases. The subphrenic free...
A Study of Meconium Aspiration Syndrome.
Chae Sup Yoo, Mee Kyung Kim, Keun Lee, Jae Sun Jung
Clin Exp Pediatr. 1988;31(11):1425-1431.   Published online November 30, 1988
The authors observed 51 cases of meconium aspiration syndrome in newborns who were bom at Ewha Womans University Hospital during the period of January 1986 through May, 1987. The results are summarized as follows: 1) The incidence of meconium aspiration syndrome was 1.6% (51 cases). 2) There was a significantly greater incidence of developing meconium aspiration syndrome in meconium stained babies who had toxemia mothers and low...
A Case of Pulmonary Squestration.
Byung Sook Park, Jin Oh Kim, Beyong Sang Choi, Chan Uhng Joo, Dae Yeol Lee
Clin Exp Pediatr. 1988;31(10):1390-1393.   Published online October 31, 1988
Pulmonary sequestration is an uncommon congenital malformation charcterized by the presence of nonfunctioning lung tissue which usually has no communciation with the normal bronchial tree and which receives it's blood supply from an anomalous systemic artery instead of pulmonary arterial branch. We have experienced a case of pulmonary sequestration. The patient was 5 10/12 years old girl with the complaint of fever, cough, Chest films...
Diagnostic Value of the Lung Perfusion Scan in Foreign body Aspiration.
Ki Hong Park, Chong Woo Bae, Byoung Soo Cho, Sa Joon Chung, Yong Mook Choi, Chang Il Ahn, Sun Wha Lee, Chang Il Cha
Clin Exp Pediatr. 1988;31(10):1301-1307.   Published online October 31, 1988
Lung perfusion scan was performed on 5 young children suspected as foreign body aspiration who had been admitted on the Department of Pediatrics, Kyung Hee University Hospital from May 1986 to January 1988. The results were as follows: 1) All children had been showed perfusion defect as compatible as acute obstructive lung disease by lung perfusion scan and foreign bodies in bronchial tree were proved on...
Diagnosis of Meconium Aspiration by Spectrophotometric Analysis of Urine.
Chang Yul Kim, Hye Kyung Bae, Mee Kyung Namgoong, Baek Keun Lim, Joong Soo Kim
Clin Exp Pediatr. 1988;31(10):1275-1280.   Published online October 31, 1988
We measured optical density of aqueous extracts of meconium and meconium stained amniotic fluid at 390 nm, 405 nm, 420 nm, 435 nm, 450 nm by spectrophotometry. We also applied the spectrophotometric method to the urine from 25 infants with clinical sign of meconium aspiration and from normal infants. The absorption band at 450 nm observed on the spectra of urine was estimated as...
A Study on Prognostic Factors of Meconium Aspiraion Syndrome.
Oh Kyung Lee, Hong Chul Lee, Wan Seoub Kim, Myung Ho Lee
Clin Exp Pediatr. 1988;31(9):1114-1119.   Published online September 30, 1988
We observed 42 cases of neonates, who were diagnosed as having Meconium aspiration syndrome in neonatal intensive care unit of Presbyterian Medical Center from July 1984 to May 1987. The followings were obtained: 1) The incidence of Meconium aspiration syndrome was 0.6% of all deliveries and 7.4% of meconium stained babies. 2) The geatational age was over 37 weeks in all cases and the body weight was...
Statistical Assessment on Chromosomal Aberrations observed on Childhood.
Seong Ho Kim, Jeh Hoon Shin, Soo Jee Moon, Hahng Lee, KeunSoo Lee, Youl Hey Cho, Myung So Ryu, Young Kyun Paik
Clin Exp Pediatr. 1988;31(8):977-983.   Published online August 31, 1988
Chromosomal studies were carried out in 730 patients at the Dept, of Pediatrics and Genetics, Hanyang University Hospital, form December 1979 to April 1986. A statistical assessment was carried out in 244 cases who have chromosomal aberrations. The following results were obtained: 1) Chromosomal aberrations were observed in 244 cases among 730 cases, so the propotion of chromosomal aberrations was 33%. 2) Age distribution revealed 53% of chromosomal...
Noninvasive Estimation of Systemic and Pulmonary Blood flow and the Ratio of Pulmonary to Systemic flow by Two-Dimensional Doppler Echocardigraphy.
Woo Tack Kim, Ki Ho Kim, Haeng Mi Kim, Snag Bum Lee
Clin Exp Pediatr. 1988;31(7):881-891.   Published online July 31, 1988
This study was designed to assess the accuracy and problems of noninvasively measuring right and left cardiac output at various sampling sites by range gated pursed Doppler echocardiography. High correlations were found between Fick-and Doppler-derived measurements of systemic and pulmonary flow as well as the pulmonary to systemic flow ratio in 21 patients undergoing cardiac catheterization (systemic flow [n=21] r=0.81; plulmonary flow [n=29], r=0.78;Qp/Qs...
Visual Motor Integration Abilities of Children with Learning Disorders.
Chang Jun Coe, Young Hyuk Lee, Jung Keun Kim
Clin Exp Pediatr. 1988;31(3):339-347.   Published online March 31, 1988
Children with learning problems are known to a social, educational as well as neurological problems. Learning disorder is usually defined as following children with normal intelligence and without serious psychological problems experiencing serious degree of difficulty to acquire a proper skill to learn, reading, writing and calculation. These children are usually hyperactive, easily distractable, may manifests defect in visual motor integration and various soft neurologic signs. As...
Comparison of Pulmonary and Systemic Blood Flow and Ratio of Pulmonary Blood Flow to Systemic Blood Flow Obtained by Pulsed Wave Doppler Echocardiography and Fick Method.
Sung Gy Jin, Myeng Hee Cha, Kyeng Sook Cho, Doo Sung Moon
Clin Exp Pediatr. 1987;30(9):982-989.   Published online September 30, 1987
This study was designed to assess the accuracy of pulsed wave Doppler echocardiographic measurement of pulmonary blood flow(Qp), systemic blood flow(Qs) and the ratio of pulmonary blood flow to systemic blood flow(Qp/Qs) to compare with Fick method. Seventeen patients with ventricular septal defect, aged 10 months to 14 years, participated for this study, and Doppler echocardiograghic examinations using the Aloka SSD-880 were performed. Two dimensional...
Cytogenetic Study on Chromosome Aberration in Children.
Chong Woo Bae, Chang Il Ahn, Bo Hoon Oh, Kap Soon Ju
Clin Exp Pediatr. 1987;30(6):633-639.   Published online June 30, 1987
We have conducted a retrospective study on chromosomal aberrations in children, aged under 15 years old, who had been refered to cytogenetic laboratory at Kyung Hee University Hospital from 1977 to 1986 Base upon the Karyotypes of lymphocytes and chart records, the following results were obtained; 1) Chromosomal aberrations of various types were found in 101 cases in children. 2) Age distribution revealed 65.3% were under the...
Case Report
One Case of a 18-Year-Old Boy with Domplete D-Transposition of the Great Arteries.
Tae Kyoung Kim, Bong Shin Lee, Byoung Hai Ahn, Young Hi Yoo, Hyun Suk Lee, Wook Youm
Clin Exp Pediatr. 1987;30(5):569-576.   Published online May 31, 1987
Without the appropriate treatment, infants bom with transposition of the great arteries rarely survive the first year of life. But modern aggressive palliative and corrective surgical interventions can provide such infants with considerable hope for aldolescent and adult life. In this report, we present one case of a 18-year-old boy having complete D-transposition of the great arteries with atrial septal defect (S.D.D), who was...
Original Article
Three Cases of Spontaneous Neonatal Gastric Perforation.
Wha Mo Lee, Hye Jin Lim, Son Sang Seo, Jung Woo Yang
Clin Exp Pediatr. 1987;30(4):450-455.   Published online April 30, 1987
Three cases of spontaneous neonatal gastric perforation seen at II Sin Christian Hosp, between 1981 and 1985 were seen in all reported with brief literature review. Of the three cases, two occurred in males and one in female. One case was prematurity and other two cases were small for gestational age. All perforations occurred within first five days. Respiratory difficulty and abdominal distension with radiographic...
The Effect of Intravenous Dextrose Water Given to Mother During Labor on Sodium Concentration of Maternal and Cord Serum.
Soo Kyung Chung, Dong Suk Suh, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1986;29(8):840-844.   Published online August 31, 1986
We studied the influence of intravenous electrolyte-free dextrose solution given to the mother during labor on the change of maternal and cord serum concentrations and the incidence of hyponatremia in 109 mothers and their newborns. 1) Na+ concentrations of maternal and cord serum in study group given intravenous electrolyte free dextrose solutions were 134.57土2.43 and 134.54±2.95, which was significantly lower,...
Estimation of Glomerular Filtration Rate from Plasma Creatinine and Height in Premature and Fullterm Neonates.
Yeong Jee Kim, Keun Lee
Clin Exp Pediatr. 1986;29(7):723-729.   Published online July 31, 1986
In clinical practice, creatinine clearance(Ccr) remains the most commonly used laboratory assessment of glomerular function despite methodological and technical problems of urine collection. Schwartz et al. in 1976,reported that an accurate estimate of glomerular filtration rate (GFR) could be obtained from the simple determinations of plasma creatinine (Per) and body length(L):GFR(ml/min/1.73cm2)=k• L(cm)/Pcr(mg/100ml), (k=constant). The purpose of this investigation is to compare...
Calcium, Phosphorus, and Magnesium contents of Breast Milk.
In Bock Lee, Kwang Rhun Koo, Chang Soo Ra
Clin Exp Pediatr. 1985;28(12):1216-1220.   Published online December 31, 1985
In order to determine the concentration of Ca, P, and Mg of breast mik and the alterations of their concentrations during the period of lactation, the authors studied the concentrations of Ca, P, and Mg of breast milk from 68 Korean healthy nursing mothers who delivered at term. Ca, P, and Mg concentration of breast milk were measured by calorimetric...
A Study of Measurement of Physical Development and Cardiothoracic Ratio in the Asthmatic Children.
Hee Dae Park, Ki Young Lee
Clin Exp Pediatr. 1985;28(8):756-765.   Published online August 31, 1985
Pediatric asthma is characterized by high incidence and symptoms of severe respiratory difficulty and causes great suffering by the patients due to the chronicity and the recurrent nature of the disorder. In addition, growth and development of the child are hindered and creates problems in both the psychological and education aspects of life. Changes in the lung capacity in asthmatic...
Clinical Observation of Profiles of Serologic Markers in Hepatitis B.
H Y Ahn, S T Kim, S G Cho, Y Y Choi, J S Ma, C Sohn
Clin Exp Pediatr. 1985;28(7):653-662.   Published online July 31, 1985
Serologic markers of hepatitis B virus were detected by Enzymeimmunoassay in acute(88 cases in 68 patients) and chronic (19 cases in 6 patients) hepatitis B. 1)Positive rate of HBsAg was highest (acute 64.5%, chronic 89.4%) in 5 serologic markers and AntiHBe or AntiHBs were not detected in chronic cases. 2)18 serologic profiles (I~XXIII) were observed, of these common type was...
Case Report
Pulmonary Sequestration.
J M Ryu, K A Ree, C H Yoon, S H Choi, K G Cho
Clin Exp Pediatr. 1985;28(6):593-596.   Published online June 30, 1985
The pulmonary sequestration is an uncommon congenital anomaly characterized by the presence of a part of lung tissue which is supplied by an aberrent artery from the aorta or its branch and usually has no communication with the normal bronchial tree. This is a relatively uncommon anomaly that requires arteriography for definitive diagnosis. We have experienced one case of pulmonary...
A Case of Spontaneous Gastric Perforation in the Newborn.
Ran Suh, Gui Sook Choi, Hye Lyung Baik, Hyo Jung Kim, Sung Woo Shin
Clin Exp Pediatr. 1985;28(6):587-592.   Published online June 30, 1985
A case of multiple spontaneous gastric perforations in the premature newborn was experienced at the Han II hospital. The diagnosis was suspected by sudden abdominal distension and was estabilished by demonstration of free air in the peritoneal cavity in the plain abdominal X-ray film. The patient expired after 2 hours of abdominal distension on the first day of life. The...
Original Article
Pulmonary Infiltration in Rotaviral Gastroenteritis.
Wan Sup Kwak, Wang Bock Lee, Haeng Mi Kim, Ja Hoon Koo
Clin Exp Pediatr. 1985;28(5):448-454.   Published online May 31, 1985
A clinical study was conducted to determine the frequency and degree of pulmonary infiltration in patients with rotaviral gastroenteritis. Thirty-three children with Rotazyme test positive gastroenteritis were enrolled in the study group, who had been admitted to the Pediatric Department of Kyungpook National University Hospital from September, 1983 to December, 1983. The following results were obtained: Vomiting and signs/symptoms of...
Case Report
A Case of Spontaneous Gastric Perforation of the Newborn.
Sung Won Kim, Sang Wook Song, Kyung Tae Kim, Jung Hee Lee
Clin Exp Pediatr. 1985;28(1):68-72.   Published online January 31, 1985
This is acase report of the gastric perforation occured in a 4 days old full-term normal bady. She had been well until 4 days of age, when vomitting was noted, and cynosis, respiratory distress, progressive abdominal distension were developed, rapidly. X-ray finding of the abdomen revealed large amount of free air under the both diaphragm, strongly suggesting the perforation of GI...
Original Article
Spontaneous Pneumothorax in the Newborn.
Dong Gwan Han
Clin Exp Pediatr. 1985;28(1):16-24.   Published online January 31, 1985
A retrospective 13 medical records of symptomatic and spontaneous pneumothorax of newborn has been reviewed, which occurred during last 13 years from Jan. 1971 through Dec. 1983 at Pediatric Department of Yonsei Medical School. Spontaneous pneumothorax was defined one with pneumothorax which was not given positive pressure or intubation. And following results W6re obtained; 1)The incidence of spontaneous pneumothorax in...
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